Protein complex info
Complex group namePcG and PcG-like
Complex nameRING2-L3MBTL2
Genes in complexCBX3#99, E2F6#193, (HDAC1#259|HDAC2#262), L3MBTL2#358, MGA#392, PCGF6#471, (RING1#568|RNF2#572), (RYBP#586|YAF2#771), TFDP1#702, WDR5#764
Alternative namesPRC1.6
Proteins involvedRING2, RYBP/YAF2, L3MBTL2, E2F6, PCGF6, CBX3, HDAC1/HDAC2, Dp-1, WDR5, MGA
Uniprot IDs of involved proteins
CBX3_HUMAN, E2F6_HUMAN, (HDAC1_HUMAN|HDAC2_HUMAN), LMBL2_HUMAN, MGAP_HUMAN, PCGF6_HUMAN, (RING1_HUMAN|RING2_HUMAN), (RYBP_HUMAN|YAF2_HUMAN), TFDP1_HUMAN, WDR5_HUMAN
PMID for reference on complex compositionPMID:22325352, PMID:24217316
FunctionPolycomb like complex
PMID for reference on functionPMID:22325352, PMID:24217316
Target molecule typehistone
Specific targetH2AK119
ProductH2AK119ub1
Target UniProt IDH2A1_HUMAN, H2A1A_HUMAN, H2A1B_HUMAN, H2A1C_HUMAN, H2A1D_HUMAN, H2A1H_HUMAN, H2A1J_HUMAN, H2A2A_HUMAN, H2A2B_HUMAN, H2A2C_HUMAN, H2A3_HUMAN, H2AB1_HUMAN, H2AB2_HUMAN, H2AJ_HUMAN, H2AV_HUMAN, H2AW_HUMAN, H2AX_HUMAN, H2AY_HUMAN, H2AZ_HUMAN
PMID for reference on targets and products#
Comment#
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