HGNC approved symbol | DDB2 |
HGNC ID | HGNC:2718 |
HGNC approved name | damage-specific DNA binding protein 2, 48kDa |
Entrez gene ID | GeneID:1643 (SSTAR profile) |
UniProt AC (human) | Q92466 |
UniProt ID (human) | DDB2_HUMAN |
Pfam domains | WD40 PF00400 (234-271, 284-316) |
MGI symbol | Ddb2 |
MGI ID | MGI:1355314 |
UniProt AC (mouse) | Q99J79 |
UniProt ID (mouse) | DDB2_MOUSE |
HGNC gene family tag | WDR |
HGNC gene family description | WD repeat domain containing |
Function | Histone modification write cofactor |
Modification | Histone ubiquitination |
PMID for information on function | PMID:16678110 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:16678110 |
Comment | DDB1-CUL4ADDB2 E3 in vivo targets histone H2A for ubiquitination at UV-damage DNA sites, where DDB2 serves as the substrate receptor. |
Status of entry | # |