HGNC approved symbol HGNC ID Alternative names HGNC approved name Entrez gene ID HGNC gene family tag HGNC gene family description Function PMID for reference on function Target molecule type Specific target Target UniProt ID
PMID for reference on targets and products Comment Status of entry
17A
(details) 		# 17A # # # # RNA binding 20888417 RNA pre-mRNA # 20888417 Splicing shift from full-length to shorter GABAB R2 variant by RNA-RNA duplex with GPR51 New
51A
(details) 		# 51A # # # # RNA binding 22996644 RNA pre-mRNA # 22996644 Splicing shift from A to variant B by formation RNA-RNA duplex with an intronic sequence of the pre-mRNA SORL1 New
A1BG-AS1
(details) 		37133 FLJ23569 A1BG antisense RNA 1 503538 # Antisense RNAs miRNA sponging 30556161, 34115333 RNA miR-216a-5p, miR-485-5p # 30556161, 34115333 Acts as molecular sponge of miR-216a-5p, miR-485-5p. Supresses cell prolifiration and invasion. New
AC005592.2
(details) 		# AC005592.2 # # # # # 33622275 # # # 33622275 Positively regulates the expression of OLFM4 New
AC016747.3
(details) 		# AC016747.3 # # # # # # # # # # New
AC091729
(details) 		# AC091729 # # # # Splicing factor recruitment 32039035 Protein SRSF2 SRSF2_HUMAN 32039035 Regulates SRSF2 splicing factor to play a carcinogenic role. New
AIRN
(details) 		34515 AIR, NCRNA00088, IGF2RAS, IGF2R-AS1 antisense of IGF2R non-protein coding RNA 100271873 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, Transcription machinery interference 29685978, 18988810 DNA, Protein EHMT2 EHMT2_HUMAN 29685978, 18988810 Recruits PRC2 to distal genes Slc22a2 and Slc22a3. Recruits G9a and promotes H3K9me3 histone modification causing gene silencing. Transcription  of Airn in cis reduct accessibility of its overlapping protein-coding gene Igf2r, causing the displacement of Pol II from the overlapping promoter. New
ARAP1-AS1
(details) 		39993 # ARAP1 antisense RNA 1 100874075 # Antisense RNAs miRNA sponging 32110804 RNA miR-2110 # 32110804 ARAP1-AS1 functions as a ceRNA for miR-2110 to upregulate HDAC2. New
Antisense transcript at each Pcdhα first exon
(details) 		# Antisense transcript at each Pcdhα first exon # # # # Promoter switching 30955885 # # # 30955885 Transription of antisence RNA promotes demethylation of the CTCF binding sites proximal to each promoter and regulates promoter choice for Pcdhα transcription. New
BAALC-AS1
(details) 		50461 lncFZD6, FZD6-DT BAALC antisense RNA 1 100499183 # Antisense RNAs Chromatin remodeler recruitment 29535420 Protein SMARCA4 SMCA4_HUMAN 29535420 LncFZD6 interacts with BRG1-embedded SWI/SNF complex and recruits it to FZD6 promoter, therefore activating its transcription. New
BLACAT1
(details) 		48597 linc-UBC1, LINC00912, onco-lncRNA-30 BLACAT1 overlapping LEMD1 locus 101669762 # # Histone modifier recruitment, miRNA sponging 28885863, 23688781 RNA, Protein miR-144, EZH2 EZH2_HUMAN 28885863, 23688781 Acts as molecular sponge of miR-144. Regulates expression of genes in trans via binding PRC2. Regulates proliferation, tumorigenicity and metastatic potential of bladder cancer cells. New
BOLA3-DT
(details) 		42922 BOLA3-AS1 BOLA3 divergent transcript 100507171 # Divergent transcripts # # # # # # New
BlackMamba
(details) 		# BlackMamba # # # # Chromatin remodeler recruitment 32123306 Protein HELLS HELLS_HUMAN 32123306 BlackMamba interacts with the DNA helicase HELLS controlling its recruitment to the promoter regions, therefore controling the neoplastic phenotype of ALK - anaplastic large cell lymphoma New
Braveheart
(details) 		# Braveheart # # # # TF recruitment 28095922, 27716479 Protein CNBP CNBP_HUMAN 28095922, 27716479 Regulator of cardiac lineage specification and differentiation via binding transcription factor CNBP. New
CASC15
(details) 		28245 LINC00340, lnc-SOX4-1 cancer susceptibility 15 401237 # Long non-coding RNAs with non-systematic symbols miRNA sponging 31695430 RNA miR-221 # 31695430 CASC15 inhibits ovarian cancer progression through regulation of miR-221/ARID1A axis. New
CCAT1
(details) 		45128 CARLo-5, onco-lncRNA-40 colon cancer associated transcript 1 100507056 # Antisense RNAs Histone modifier recruitment, Modulation of chromatin functions, Chromatin looping 24662484 DNA, Protein CTCF, hnRNPK CTCF_HUMAN 24662484 Regulates MYC transcription and promotes long-range chromatin looping, interacts with CTCF and regulates its binding to chromatin New
CD27-AS1
(details) 		43896 # CD27 antisense RNA 1 678655 # Antisense RNAs miRNA sponging 34006845 RNA miR-224-5p # 34006845 Acts as a molecular sponge of miR-224-5p New
CDKN2B-AS1
(details) 		34341 ANRIL, RP11-145E5.4, NCRNA00089, p15AS, CDKN2B-AS, PCAT12 CDKN2B antisense RNA 1 100048912 # Antisense RNAs Chromatin remodeler recruitment, Histone modifier recruitment 29685978, 33353982, 30870006 Protein YY1; BCL11 TYY1_HUMAN, BC11A_HUMAN, BC11B_HUMAN 29685978, 33353982 Recruits Polycomb repressive complexes to promoters of CDKN2A and CDKN2B to inhibit their expression in cis and to regulate distant genes in trans. Interacts with BCL11A and mediates MAP4K1 transcription. New
CHASERR
(details) 		48626 LINC01578 CHD2 adjacent suppressive regulatory RNA 100507217 # Long non-coding RNAs with non-systematic symbols # 31704914 # # # 31704914 Represses Chd2 expression and broadly regulates CHD2 targets New
CIrcSMARCA5
(details) 		# # # # # # Splicing factor recruitment 29415469 Protein SRSF1 SRSF1_HUMAN 29415469 Interacts with SRSF1 and promotion of the anti-angiogenic splicing isoforms of VEGF-A New
DALIR
(details) 		51429 DALI DNMT1-associated long intergenic non-coding RNA 104940698 # Long non-coding RNAs with non-systematic symbols DNA modifier recruitment 25415054 Protein DNMT1 DNMT1_HUMAN 25415054 Interacts with the DNMT1 DNA methyltransferase and regulates DNA methylation status of CpG island-associated promoters in trans gene activation. New
DANCR
(details) 		28964 ANCR, AGU2, lncRNA-ANCR differentiation antagonizing non-protein coding RNA 57291 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 31383847 Protein EZH2 EZH2_HUMAN 31383847 Binds EZH2 and promotes H3K27me3 histone modification. Regulates proliferation and migration-related genes. New
DDX11-AS1
(details) 		44176 CONCR, SCAT4 DDX11 antisense RNA 1 100506660 # Antisense RNAs Modulation of protein functions 27477908 Protein DDX11 DDX11_HUMAN 27477908 Modulates abiity of DDX11 to function at DNA replication fork. Increases its ATPase activity and binding to DNA replicating regions New
DGCR5
(details) 		16757 NCRNA00037, LINC00037, X91348, DGS-A, POM121L5P, DGS-B, DGCR9, DGCR10 DiGeorge syndrome critical region gene 5 26220 # Long non-coding RNAs with non-systematic symbols Chromatin remodeler recruitment 30238982 Protein ARID1A ARI1A_HUMAN 30238982 DGCR5 interacts with ARID1A to promote P21 transcription. New
DINOL
(details) 		53146 DINO damage induced long noncoding RNA 108783646 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 27668660 Protein TP53 P53_HUMAN 27668660 Forms complex with p53, thereby activates its target genes. Causes cell cycle arrest and induces DNA damage New
DLEU1
(details) 		13747 LEU1, XTP6, NCRNA00021, LINC00021, BCMS1, DLB1, BCMS deleted in lymphocytic leukemia 1 10301 # Long non-coding RNAs with non-systematic symbols Chromatin remodeler recruitment 28598010, 30098595 Protein SMARCA1 SMCA1_HUMAN 28598010, 30098595 DLEU1 recruits SMARCA1 at KPNA3 promoter to promote KPNA3 activation in CRC. Upregulates SMARCD1 by repression of miR‐490‐3p. New
DNM3OS
(details) 		41228 # DNM3 opposite strand/antisense RNA 100628315 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, TF recruitment, miRNA sponging 33472090, 31992960, 31526393, 32463958, 31694982, 30770102 RNA, Protein miR-126, miR-134-5p, miR-204-5p, miR-29a, miR-361, KDM6B, Snail KDM6B_HUMAN, SNAI1_HUMAN 33472090, 31992960, 31526393, 32463958, 31694982, 30770102 Acts as a molecular sponge of miR-126, miR-134-5p, miR-204-5p, miR-29a, miR-361. Interacts with KDM6B and provides reduction of H3K27me3 which is accelerate growth and metastasis. Binds transcription factor Snail, therefore regulates invasion and migration abilities of cancer cells. New
DRAIC
(details) 		27082 # downregulated RNA in cancer, inhibitor of cell invasion and migration 145837 # Long non-coding RNAs with non-systematic symbols Protein binding 32351584 Protein UCHL5 UCHL5_HUMAN 32351584 DRAIC regulates the ubiquitination level of NFRKB by interaction with UCHL5. New
DSCAM-AS1
(details) 		40197 M41 DSCAM antisense RNA 1 100506492 # Antisense RNAs 32503257 32503257 New
EMX2OS
(details) 		18511 NCRNA00045, EMX2-AS1 EMX2 opposite strand/antisense RNA 196047 # Long non-coding RNAs with non-systematic symbols Protein binding, miRNA sponging 32801740, 32273754 RNA, Protein miR-654, Fus FUS_HUMAN 32801740, 32273754 Directly binds to miR-654 and suppresses its expression. Binds FUS protein and had a synergy effect with FUS protein on cGMP-PKG-mediated cell functions New
FAS-AS1
(details) 		37128 FASAS, FAS-AS, SAF FAS antisense RNA 1 100302740 # Antisense RNAs Splicing factor recruitment, RNA binding 26885613 RNA, Protein pre-mRNA FAS, SPF45 SPF45_HUMAN 26885613 Provides exon 6 skipping by forming RNA-RNA duplex with the target pre-mRNA FAS and recruiting SPF45 New
FGD5-AS1
(details) 		40410 # FGD5 antisense RNA 1 100505641 # Antisense RNAs miRNA sponging 34221989, 31332696, 31919528 RNA miR-497-5p, miR-302e, hsa-miR-107 # 34221989, 31332696, 31919528 Acts as molecular sponge of miR-497-5p, miR-302e, hsa-miR-107 (up-regulate FGFRL1). Regulates cell prolifiration and migration. As ceRNA inhibiting CDCA7 degradation New
FIRRE
(details) 		49627 LINC01200 firre intergenic repeating RNA element 286467 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, Chromatin looping 29685978, 25887447 Protein hnRNPU, CTCF CTCF_HUMAN, HNRPU_HUMAN 29685978, 25887447 Histone modifier recruitment, Chromatin looping New
FOXD3-AS1
(details) 		40241 pasFOXD3, FAST FOXD3 antisense RNA 1 100996301 # Antisense RNAs Protein sequestration 32259487 Protein β-TrCP FBW1A_HUMAN 32259487 Interacts with β-TrCP to prevent β-catenin degradation, activates WNT signaling New
GNAS-AS1
(details) 		24872 SANG, NESP-AS, NESPAS, GNAS1AS, NCRNA00075, GNASAS, GNAS-AS GNAS antisense RNA 1 149775 # Antisense RNAs miRNA sponging, RNA binding 33212147, 28805067 RNA mirR-615-3p, miR-4319, miR-291a-3p, miR-196a-5p, miR-23a-3p, miR-24-3p, miR-let-7a-5p, mRNA # 33212147, 28805067 Acts as molecular sponge of mirR-615-3p, miR-4319, miR-291a-3p, miR-196a-5p, miR-23a-3p, miR-24-3p and miR-let-7a-5p and involved in osteoartritis pathogenesis. Regulate expression of genes involved in peroxisomal activities via mRNA binding. New
HAND2-AS1
(details) 		48872 DEIN, NBLA00301, FLJ11539 HAND2 antisense RNA 1 79804 # Antisense RNAs Chromatin remodeler recruitment 31334575 Protein INO80 INO80_HUMAN 31334575 HAND2‐AS1 recruits the INO80 chromatin‐remodeling complex to the promoter of BMPR1A, thereby inducing its expression and leading to the activation of BMP signaling New
HELLPAR
(details) 		43984 LINC-HELLP HELLP associated long non-coding RNA 101101692 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 26173455 Protein YBX1, PCBP1, PCBP2, RPS6, RPL7 YBOX1_HUMAN, PCBP1_HUMAN, PCBP2_HUMAN, RS6_HUMAN, RL7_HUMAN 26173455 Interacts with ribosomal and splicing complex components New
HOTAIR
(details) 		33510 HOXC-AS4, HOXC11-AS1, NCRNA00072 HOX transcript antisense RNA 100124700 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 29685978, 31901481 Protein EZH2 EZH2_HUMAN 29685978, 31901481 Recruits EZH2 to silence E-Cadherin expression, thereby promoting cell migration and invasion. Represses tumor suppressor gene expression by hypermethylation of its CpG island. New
HOTTIP
(details) 		37461 NCRNA00213, HOXA-AS6, RP1-170O19.3, HOXA13-AS1 HOXA distal transcript antisense RNA 100316868 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 29685978, 21423168, 31786140 Protein WDR5, KMT2A WDR5_HUMAN, KMT2A_HUMAN 29685978, 21423168, 31786140 Activates HOXA genes via binding the adaptor protein WDR5 directly and targets WDR5/MLL complexes across HOXA, driving histone H3 lysine 4 trimethylation and gene transcription. New
HPSE eRNA
(details) 		# # # # # # Chromatin looping 29511351 Protein hnRNPU HNRPU_HUMAN 29511351 Binds looping factor hnRNPU and facilitating chromatin looping between super enhancer and HPSE promoter. New
IL-7-AS
(details) 		# IL-7-AS # # # # Histone modifier recruitment 31383742 DNA, Protein p300 EP300_HUMAN 31383742 IL-7-AS regulates H3K9Ac and H3K14Ac at gene promoters and modulates the expression of several inflammatory genes by recruiting the histone acetyltransferase p300. Thereby, facilitates the recruitment of the SWI/SNF complex. New
JPX
(details) 		37191 NCRNA00183, ENOX, LINC00183, DCBALD06 JPX transcript, XIST activator 554203 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions, miRNA sponging 23791181, 31253987, 30091314, 34856126 RNA, Protein CTCF, miR-145-5p, miR-155-5p CTCF_HUMAN 23791181, 31253987, 30091314 Jpx bind CTCF and regulates its anchor site selection therefore controlling formation of chromosome loops. Jpx activates Xist by evicting CTCF from one Xist allele. New
KCNQ1OT1
(details) 		6295 KvDMR1, KCNQ1-AS2, KvLQT1-AS, LIT1, NCRNA00012 KCNQ1 opposite strand/antisense transcript 1 10984 # Long non-coding RNAs with non-systematic symbols Chromatin remodeler recruitment, Histone modifier recruitment, DNA modifier recruitment 20573698, 18951091 Protein, DNA EZH2, SUZ12, EHMT2, DNMT1 EZH2_HUMAN, SUZ12_HUMAN, EHMT2_HUMAN, DNMT1_HUMAN 20573698, 18951091 Involved in epigenetic silencing by recruiting EHMT2, PRCs, Dnmt1. New
KDM2B-DT
(details) 		53287 # KDM2B divergent transcript 101928346 # Divergent transcripts Chromatin remodeler recruitment, Protein sequestration 30865882, 26590717 Protein SRCAP, SATB1, CTCF SRCAP_HUMAN, SATB1_HUMAN, CTCF_HUMAN 30865882, 26590717 KDM2B-DT activates Zbtb3 and Zfp292 by promoting the assembly and ATPase activity of SRCAP and NURF complexes. New
Khps1
(details) 		# Khps1 # # # # Histone modifier recruitment 26590717 DNA, Protein EP300, CREBBP EP300_HUMAN, CBP_HUMAN 26590717 Khps1 recruitis the HAT p300/CBP to the SPHK1 promoter, therefore ensures E2F1 binding and enhances transcription. New
LASTR
(details) 		54143 LINC02657 lncRNA associated with SART3 regulation of splicing 105376382 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 31956895 Protein SART3 SART3_HUMAN 31956895 Promotes splicing efficiency by interacting with SART3 New
LCTS5
(details) 		# LCTS5 # # # # Modulation of protein functions 32305524 Protein INO80 INO80_HUMAN 32305524 LCTS5 inhibits INO80 and transcription of INO80 mediated lung cancer-associated genes. New
LINC00163
(details) 		33165 C21orf134, NCRNA00163, NLC1-A, NLC1A long intergenic non-protein coding RNA 163 727699 LINC Long intergenic non-protein coding RNAs Chromatin remodeler recruitment 31646568 DNA, Protein ARID1A ARI1A_HUMAN 31646568 LINC00163 is enriched on the TCF21 promoter and recruits ARID1A to it, thereby increases TCF21 expression. New
LINC00511
(details) 		43564 onco-lncRNA-12 long intergenic non-protein coding RNA 511 400619 LINC Long intergenic non-protein coding RNAs Histone modifier recruitment, miRNA sponging 32368318, 32196597, 32092829, 31646568, 31417312, 31395854 RNA, DNA, Protein KDM1A, EZH2, miR-124-3p, miR 150-5p, miR-153-5p, miR-185-3p KDM1A_HUMAN, EZH2_HUMAN 32368318, 32196597, 32092829, 31646568, 31417312, 31395854 Acts as molecular sponge of miR-124-3p, miR 150-5p, miR-153-5p, miR-185-3p. In the present study, Binds KDM1A and EZH2. It inhibited expressions of p21, p57 LATS2 and KLF2 by binding to their promoter region. Interaction with EZH2 leads to recruitment PRC2 to mediate histone DNA Methylation, contributing to the G1/S transition to sustain cell proliferation. Maintaines the stability of Snail by impeding its ubiquitination and degradation by the BTRC E3 ubiquitin protein. New
LINC00668
(details) 		44328 # long intergenic non-protein coding RNA 668 400643 LINC Long intergenic non-protein coding RNAs miRNA sponging 32249890 RNA miR-532-5p # 32249890 LncRNA LINC00668 promotes cell proliferation, migration, invasion ability and EMT process in hepatocellular carcinoma by targeting miR-532-5p/YY1 axis New
LINC00702
(details) 		44676 # long intergenic non-protein coding RNA 702 100652988 LINC Long intergenic non-protein coding RNAs Histone modifier recruitment, miRNA sponging 30849635, 30840927 RNA, Protein EZH2, miR-4652-3p EZH2_HUMAN 30849635, 30840927 Interacts with EZH2 to inhibit the transcription of KLF2. May act as a ceRNA for miR-510. Acts as molecular sponge of miR-4652-3p to upregulate ZEB1. New
LINC00862
(details) 		21901 C1orf98, SMIM16 long intergenic non-protein coding RNA 862 554279 LINC Long intergenic non-protein coding RNAs # # # # # # # New
LINC00899
(details) 		48583 # long intergenic non-protein coding RNA 899 100271722 # Long non-coding RNAs with non-systematic symbols miRNA sponging 32157707 RNA miR-744-3p # 32157707 LINC00899 modulated AML cell proliferation and apoptosis via miR-744-3p/YY1 axis. New
LINC00963
(details) 		48716 MetaLnc9 long intergenic non-protein coding RNA 963 100506190 LINC Long intergenic non-protein coding RNAs miRNA sponging 32554858, 31477326, 32494199 RNA miR-542-3p, miR-1193, miR-766-3p # 32554858, 31477326, 32494199 Acts as a molecular sponge of miR-542-3p, miR-1193, miR-766-3p New
LINC00968
(details) 		48727 # long intergenic non-protein coding RNA 968 100507632 LINC Long intergenic non-protein coding RNAs Histone modifier recruitment, miRNA sponging 30485507, 30197001, 30791958, 33147570, 33065511, 33159015, 31213129 RNA, Protein EZH2, HEY1, hsa-miR-423-5p, miR-3658, miR-21-5p EZH2_HUMAN, HEY1_HUMAN 30485507, 30197001, 30791958, 33147570, 33065511, 33159015, 31213129 Recruits EZH2 to inhibit p21 expression via binding EZH2 and H3K27me3 of p21 promoter. Inhibits Wnt2/β-catenin signaling pathway via recruitment of HEY1 and silencing Wnt2. Inhibits miR-9-3p expression in an endothelial cell and promotes their proliferation and migration. Acts as molecular sponge of hsa-miR-423-5p, miR-3658, miR-21-5p. New
LINC01133
(details) 		49447 lncRNA-PAGBC long intergenic non-protein coding RNA 1133 100505633 LINC Long intergenic non-protein coding RNAs Protein sequestration 27443606 Protein SRSF6 SRSF6_HUMAN 27443606 Provides titration of SRSF6 splicing factor from its target genes New
LINC01410
(details) 		50702 # long intergenic non-protein coding RNA 1410 103352539 LINC Long intergenic non-protein coding RNAs miRNA sponging 32314193 RNA miR-23c # 32314193 LINC01410 functions as a ceRNA for miR-23c to upregulate CHD7 and therefore promotes endometrial cancer progression. New
LINC01503
(details) 		51184 lnc-PPP2R4-5, RP11-65J3.1 long intergenic non-protein coding RNA 1503 100506119 LINC Long intergenic non-protein coding RNAs # # # # # # # New
LNCBRM
(details) 		52752 LINCR-0003, lncBRM ncRNA SMARCA2 (BRM) associated 100996645 # Antisense RNAs Modulation of protein functions 27905400 Protein SMARCA2 SMCA2_HUMAN 27905400 LncBRM associates with BRM to initiate the BRG1/BRM switch. New
LNCPRESS1
(details) 		52746 # lncRNA p53 regulated and ESC associated 1 101927721 # Long non-coding RNAs with non-systematic symbols Protein sequestration 27912097 Protein SIRT6 SIR6_HUMAN 27912097 Disrupt SIRT6 mediated de-acetylation of H3K56 and regulates ESC differentiation by safeguard pluripotency New
LUCAT1
(details) 		48498 SCAL1, SCAT5 lung cancer associated transcript 1 100505994 # Long non-coding RNAs with non-systematic symbols # 31591432 # # # 31591432 LUCAT1 is proposed to be related with PTC progression through LUCAT1/CDK1/EZH2/P57/P21/HDAC1/DNMT1/P53/BAX axis New
Linc-YY1
(details) 		# Linc-YY1 # # # # Protein sequestration 26658965, 30662806 Protein YY1 TYY1_HUMAN 26658965, 30662806 Linc-YY1 interacts with YY1 through its middle domain, to evict YY1/Polycomb repressive complex (PRC2) from target promoters, thus activating the gene expression in trans. New
Lnc-Spry1
(details) 		# Lnc-Spry1 # # # # Splicing factor recruitment 28186499 Protein U2AF65 U2AF2_HUMAN 28186499 Interacts with U2AF65 and regulates splicing New
MAGI2-AS3
(details) 		40862 ENST00000414797 MAGI2 antisense RNA 3 100505881 # Antisense RNAs Histone modifier recruitment, miRNA sponging 33231563, 32138716, 32681706, 31709544, 31910343, 31837602, 30883342, 31629962 RNA, Protein miR-31-5p, miR-25, miR-525-5p, miR-3163, miR-155, miR-141/200a, miR-374a, KDM1A KDM1A_HUMAN 33231563, 32138716, 32681706, 31709544, 31910343, 31837602, 30883342, 31629962 Acts as molecular sponge of miR-31-5p, miR-25, miR-525-5p, miR-3163, miR-155, miR-141/200a, miR-374a. MAGI2-AS3 plays an important role as a tumour suppressor by targeting Fas and FasL signalling. lncRNA MAGI2‑AS3 promotes expression of Fas and FasL in breast cancer cells. Recruits KDM1A to H3K4me2 deDNA Methylation at the RACGAP1 promoter, which ultimately decreased the expression of RACGAP1. New
MALAT1
(details) 		29665 PRO1073, MALAT-1, NCRNA00047, HCN, NEAT2, LINC00047, mascRNA metastasis associated lung adenocarcinoma transcript 1 378938 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 29685978, 28412742 RNA, Protein SC35, SR proteins, U1 snRNA, NEAT1, EZH2, SUZ12 EZH2_HUMAN 29685978, 28412742 Modulates SR protein phosphorylation in nuclear speckles. Binds EZH2 and SUZ12, which induce H3K27me3. New
MAPKAPK5-AS1
(details) 		24091 FLJ39616 MAPKAPK5 antisense RNA 1 51275 # Antisense RNAs miRNA sponging 32690100, 33272009 RNA miR-519e-5p. let-7f-1-3p # 32690100, 33272009 Acts as molecular sponge of miR-519e-5p. let-7f-1-3p, Up-regulates p21 and increase proliferation. New
MATN1-AS1
(details) 		40364 # MATN1 antisense RNA 1 100129196 # Antisense RNAs miRNA sponging 31667976 RNA miR-200b/c/429 # 31667976 MATN1-AS1 functions as a ceRNA for miR-200b/c/429 to upregulate CHD1 New
MEG3
(details) 		14575 GTL2, NCRNA00023, LINC00023, onco-lncRNA-83 maternally expressed 3 55384 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, Splicing factor recruitment, TF recruitment, miRNA sponging, DNA modifier recruitment 30793226, 30887511, 31863691, 31328388, 29024030, 33284093, 31790140, 32420340, 30476192, 33180644 DNA, RNA, Protein PTBP3, EZH2, DNMT1, KLF4, miR-421 miR-135, miR-147, miR-6088, miR-223 PTBP3_HUMAN, EZH2_HUMAN, DNMT1_HUMAN, KLF4_HUMAN 30793226, 30887511, 31863691, 31328388, 29024030, 33284093, 31790140, 32420340, 30476192, 33180644 Act as molecular sponge of miR-421 miR-135, miR-147, miR-6088, miR-223. Boosts the expression and maturation of miR122 which is decreased PKM2 levels and therefore suppressed expression of cyclin D1 and C-Myc. Negatively regulates miR-664 expression resulting in increased ADH4. GA-rich motifs able to direct MEG3 to its target genes PRC2 and H3K27me3 and regulate TGF-β pathway genes. In association with DNMT1 controls endotgelial-mesenchymal transition in diabetic retinopathy. Facilitates H3K27 trimethylation of EN2 through binding to EZH2. Interacts with PTBP3 to regulate gene expression and endothelial function through p53 signaling. Binds KLF4 and inhibited its protein expression. New
MIAT
(details) 		33425 FLJ25967, Rncr2, gomafu, NCRNA00066, LINC00066, lncRNA-MIAT myocardial infarction associated transcript 440823 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 25145264 Protein CELF3, SF1, QKI CELF3_HUMAN, STF1_HUMAN, QKI_HUMAN 25145264 Controls retinal cell specification, stem cell differentiation and alternative splicing of schizophrenia-related genes by modulating activity of splicing factors. New
MTA2TR
(details) 		# MTA2TR # # # # TF recruitment 31410216 Protein ATF3 ATF3_HUMAN 31410216 MTA2TR transcriptionally upregulates MTA2 expression by recruiting ATF3 to the MTA2 promoter. New
MVIH
(details) 		# MVIH # # # # Protein binding 28716731 Protein ARID1A ARI1A_HUMAN 28716731 MVIH binds ARID1A and affects CDKN1A expression. New
NCYM NAT
(details) 		# NCYM NAT # # # # RNA binding 1695323 RNA mRNA # 1695323 Provides intoron I retention in NMYC by forming RNA-RNA duplex with sense transcript New
NEAT1
(details) 		30815 NCRNA00084, TncRNA, MENepsilon/beta, LINC00084, VINC nuclear paraspeckle assembly transcript 1 283131 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 31006037, 31243262, 31266852, 27556296 RNA, Protein Paraspeckle proteins, MALAT1, EP300, CREBBP, STAT3,H3, EZH2 EP300_HUMAN, CBP_HUMAN, STAT3_HUMAN, EZH2_HUMAN 31006037, 31243262, 31266852, 27556296 A scaffold lncRNA of paraspeckles. Promotes breast and skin cancer growth. Is associated with P300/CBP complex and its inhibition affects H3K27Ac and H3K27Cro located nearby to the transcription start site of many genes, including endocytosis-related genes. Mediates the binding between STAT3 and H3K27Ac. Binds EZH2 and mediates H3K27me3 enrichment at the p21 promoter. Silences miR-129-5p expression by promoting the DNA methylation of the CpG island in the miR-129 gene. New
NEXN-AS1
(details) 		31983 FLJ90637, C1orf118 NEXN antisense RNA 1 374987 # Antisense RNAs Chromatin remodeler recruitment 30589415 Protein BAZ1A BAZ1A_HUMAN 30589415 NEXN-AS1 interacts with the nuclear protein BAZ1A and reduces the level of BAZ1A to upregulate NEXN. New
NKILA
(details) 		51599 # NF-kappaB interacting lncRNA 105416157 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 30224822 Protein p65 TF65_HUMAN 30224822 Interacts with the NF-κB–IκBα complex by binding to p65 and inhibitis its activity, thereby modulates T cell activation-induced cell death New
NMR
(details) 		# NMR # # # # Chromatin remodeler recruitment 29763634 Protein BPTF BPTF_HUMAN 29763634 NMR recruits chromatin regulator BPTF to genes promoters and regulates transcription. New
NORAD
(details) 		44311 LINC00657 non-coding RNA activated by DNA damage 647979 # Long non-coding RNAs with non-systematic symbols Protein sequestration, miRNA sponging 30468715 RNA, Protein miR-590-3p, PUM1, PUM2 PUM1_HUMAN, PUM2_HUMAN 30468715 Acts as a molecular sponge of miR-590-3p. Binds PUM1 and PUM2, therefore regulates genome stability. New
NR2F1-AS1
(details) 		48622 FLJ42709 NR2F1 antisense RNA 1 441094 # Antisense RNAs miRNA sponging 30628890, 31304680 RNA miR-324-3p # 30628890, 31304680 Promotes tumorigenesis and radioresistance in breast cancer through interplay with miR-324-3p and derepression of ACK1. New
NRIP1e eRNA
(details) 		# NRIP1e eRNA # # # # Chromatin looping 23728302 DNA, Protein Cohesin STAG1_HUMAN, STAG2_HUMAN 23728302 Recruits cohesin to promote chromatin looping and activates genes in short and long distances New
PANDAR
(details) 		44048 PANDA promoter of CDKN1A antisense DNA damage activated RNA 101154753 # Long non-coding RNAs with non-systematic symbols Protein sequestration 25406515 Protein NF-YA, BMI1 NFYA_HUMAN, BMI1_HUMAN 25406515 Act as decoy of NF-YA and represses pro-apoptotic genes. Interacts with PRC1 and PRC2 and recruit them to repress the transcription of senescence-promoting genes. New
PARTICL
(details) 		50886 PARTICLE promoter of MAT2A antisense radiation-induced circulating long non-coding RNA 100630918 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 25900080 DNA, Protein PRC2 # 25900080 PARTICLE forms a DNA-lncRNA triplex upstream of a MAT2A promoter CpG island causing its suppression. Presumably, the mechanism of suppression is recruitment of PRC2 on the triplex platform. New
PCGEM1
(details) 		30145 NCRNA00071, LINC00071, PCAT9 PCGEM1 prostate-specific transcript 64002 # PCGEM1 prostate-specific transcript RNA binding 26848868 RNA hnRNP A1, U2AF65 # 26848868 Mutual bond with either hnRNP A1 or U2AF65 to promote or suppress specific AR splice variants New
PPP1R10
(details) 		9284 PNUTS, FB19, CAT53, p99 protein phosphatase 1 regulatory subunit 10 5514 PPP1R Protein phosphatase 1 regulatory subunits miRNA sponging 28825698 RNA miR-205 # 28825698 Sequesters miR-205, thereby causing upregulation of ZEB1 and ZEB2 mRNAs and promotes epithelial–mesenchymal transition New
PTCSC3
(details) 		43959 # papillary thyroid carcinoma susceptibility candidate 3 100886964 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 29561707 Protein STAT3 STAT3_HUMAN 29561707 PTCSC3 inhibits INO80 expression by negatively regulating STAT3 New
PVT1
(details) 		9709 NCRNA00079, LINC00079, onco-lncRNA-100, MIR1204HG Pvt1 oncogene 5820 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, miRNA sponging 28296507 RNA, Protein EZH2, miR-195 EZH2_HUMAN 28296507 Directly interacts with EZH2 and the complex anchors in the promoter region of miR-195. Decreases miR-195 expression via enhancing H3K27me3 levels in the miR-195 promoter region and sponging of miR-195. New
RAB30-DT
(details) 		48672 RAB30-AS1 RAB30 divergent transcript 100506233 # Divergent transcripts # # # # # # # New
RASSF1-AS1
(details) 		49091 ANRASSF1 RASSF1 antisense RNA 1 102060282 # Antisense RNAs Histone modifier recruitment 23990798 DNA, Protein PRC2 # 23990798 Recruit PRC2 and promotes silencing of tumor-supressor RASSF1A New
RMRP
(details) 		10031 CHH RNA component of mitochondrial RNA processing endoribonuclease 6023 # # miRNA sponging 30779067 miRNA miR-206 # 30779067 Interacts with regulators of post-transcriptional mitochondrial gene expression HuR and GRSF. Acts like sponge of miR-206, improving the expression of CDK9/2 and promoting lunge and bladder cancer. New
RP11-137L10.6
(details) 		# RP11-137L10.6 # # # # # # # # # # # New
RP11-221N13.3
(details) 		# RP11-221N13.3 # # # # # # # # # # # New
RP11-38L15
(details) 		# RP11-38L15 # # # # # # # # # # # New
RP11-395B7.4
(details) 		# RP11-395B7.4 # # # # # # # # # # # New
RP11-539L10.3
(details) 		# RP11-539L10.3 # # # # # # # # # # New
RP11-660L16.2
(details) 		# RP11-660L16.2 # # # # # # # # # # # New
RP6-109B7.3
(details) 		# RP6-109B7.3 # # # # # # # # # # # New
RP6-99M1.2
(details) 		# RP6-99M1.2 # # # # # # # # # # # New
SAMMSON
(details) 		49644 LINC01212 survival associated mitochondrial melanoma specific oncogenic non-coding RNA 101927152 # Long non-coding RNAs with non-systematic symbols Modulation of protein functions 27008969 Protein CARF, p32 CARTF_HUMAN, C1QBP_HUMAN 27008969 Interacts with p32 and CARF to promotes mitochondrial rRNA synthesis. Promotes cell growth. New
SBF2-AS1
(details) 		27438 # SBF2 antisense RNA 1 283104 # Antisense RNAs miRNA sponging 30912164, 31062614 RNA miR-188-5p, miR-619-5p # 30912164, 31062614 Acts as molecular sponge of miR-188-5p and miR-619-5p, therefore leads to overexpression of HDAC3. Increases H3K27m at the promoter region of P21. Increases cell prolifiration ability. New
SCHLAP1
(details) 		48603 PCAT11, LINC00913 SWI/SNF complex antagonist associated with prostate cancer 1 101669767 # Long non-coding RNAs with non-systematic symbols # 24076601, 30510238 DNA, Protein SWI/SNF # 24076601, 30510238 Presumably, competes with  the SWI/SNF complex for DNA-binding at promoter gene region thereby promotes aggressive prostate cancer. However, acoording to recent study, SCHLAP1 likely functions in a SWI/SNF independent manner. New
SERTAD4-AS1
(details) 		32019 C1orf133 SERTAD4 antisense RNA 1 574036 # Antisense RNAs # # # # # # # New
SMANTIS
(details) 		# NONHSAG028084.2, HSALNG0015754, Lnc-AAK1-2, MANTIS # 107985770 # # Chromatin remodeler recruitment, Modulation of protein functions 31222221, 28351900 DNA, Protein SMARCA4 SMCA4_HUMAN 31222221, 28351900 MANTIS binds DNA at the promoters of angiogenenic genes, thereby regulates angiogenesis. Directly interacts with BRG1, and increases its ATPase activity. Regulates SOX18, SMAD6, and COUP-TFII, ICAM-1 expression New
SNHG14
(details) 		37462 NCRNA00214, UBE3A-AS, UBE3A-ATS small nucleolar RNA host gene 14 104472715 SNHG Small nucleolar RNA non-coding host genes miRNA sponging 30611620, 33155197, 31948764, 31471872, 31570691 RNA miR-206, miR-655-3p, miR-433-3p, miR-32-5p, miR-5590-3p # 30611620, 33155197, 31948764, 31471872, 31570691 Acts as molecular sponge of miR-206, miR-655-3p, miR-433-3p, miR-32-5p, miR-5590-3p New
SNHG15
(details) 		27797 FLJ38860, MYO1GUT, Linc-Myo1g, C7orf40 small nucleolar RNA host gene 15 285958 SNHG Small nucleolar RNA non-coding host genes miRNA sponging 31636472 RNA miR-490-3p # 31636472 lncRNA-SNHG15 functions as a ceRNA for miR-490-3p to upregulate HDAC2. New
SPAG5-AS1
(details) 		41140 # SPAG5 antisense RNA 1 10050643 # Antisense RNAs miRNA sponging 31957155 RNA miR-769-5p # 31957155 SPAG5-AS1 regulates miR-769-5p/YY1 axis and induces SPAG5. New
SPAs from the imprinted region 15q11-q13
(details) 		# SPAs from the imprinted region 15q11-q13 # # # # Protein sequestration 27871485 Protein hnRNPM, RBFOX2, TDP43 HNRPM_HUMAN, RFOX2_HUMAN, TADBP_HUMAN 27871485 Sequesters hnRNPM, RBFOX2 and TDP43 and regulates mRNA splicing New
SWINGN
(details) 		# SWINGN # # # # Histone modifier recruitment 32071317 DNA, Protein SWI/SNF 32071317 Influences the ability of the SWI/SNF complexes to drive epigenetic activation of specific promoters, activates the proximal gene GAS6 and distant genes in trans New
TARID
(details) 		50506 # TCF21 antisense RNA inducing promoter demethylation 100507308 # Long non-coding RNAs with non-systematic symbols DNA modifier recruitment 30617255 DNA, Protein GADD45A GA45A_HUMAN 30617255 Recruits GADD45A and promotes demethylation of the hypermethylated TCF21 promoter in multiple types of cancer via R-loop formation New
TINCR
(details) 		14607 FLJ90734, NCRNA00036, LINC00036, onco-lncRNA-16 TINCR ubiquitin domain containing 257000 # # Protein binding 23201690 Protein STAU1 STAU1_HUMAN 23201690 Mediates stabilization and expression of differentiation associated mRNA New
TMCC1-DT
(details) 		49060 TMCC1-AS1 TMCC1 divergent transcript 100507032 # Divergent transcripts # # # # # # New
TP53COR1
(details) 		43652 lincRNAp21, linc-p21, lincRNA-p21, Trp53cor1 tumor protein p53 pathway corepressor 1 102800311 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment, DNA modifier recruitment 28425074 Protein hnRNP-K, DNMT1 DNMT1_HUMAN, HNRPK_HUMAN 28425074 Regulates reprogramming. Interacts with hnRNP-K and DNMT1, thereby block somatic cell reprogramming by CpG methylation at the promoters of a subset of genes and H3K9me3 maintenance at the promoters of pluripotency genes. New
TUG1
(details) 		26066 FLJ20618, NCRNA00080, LINC00080 taurine up-regulated 1 55000 # # Histone modifier recruitment, miRNA sponging 29016735, 31858814, 31880241, 30925453 RNA, Protein miR-299, miR-204-5p, miR-145, miR-132-3p, PRC2 # 29016735, 31858814, 31880241, 30925453 Acts as a molecular sponge of miR-299, miR-204-5p, miR-132-3p, miR‐219a‐5p and miR-145 to enhance tumor-induced angiogenesis in human glioblastoma. Up-regulated HDAC3, which reduced the acetylation of H3K9 and epigenetically inhibited expressions of anti-oxidative genes, including Bcl-xL, Prdx2, and Hsp70. Studies suggested that TUG1 can directly bind to a histone methylated transferase PRC2, therefore regulate the expressions of target genes. New
Transcript from DHFR minor promoter
(details) 		# transcript from DHFR minor promoter # # # # Transcription machinery interference 17237763 DNA # # # Forms highly specific and stable triplex structures on the DHFR major promoter and impede the formation of the preinitiation complex. New
UCHL1-DT
(details) 		40600 AS-Uchl1, UCHL1-AS1 UCHL1 divergent transcript 101410542 # Divergent transcripts RNA binding 23064229 mRNA Uchl1 mRNA # 23064229 Activates Uchl1 mRNA translation New
UMLILO
(details) 		51824 # upstream master lncRNA of the inflammatory chemokine locus 114515515 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 30531872 Protein WDR5, KMT2A WDR5_HUMAN, KMT2A_HUMAN 30531872 Activates transcription of CXCL chemokines. Primes transcription of immune genes during trained immunity New
WSPAR
(details) 		51639 TCONS_00009511-XLOC_004555, lncTCF7 WNT signaling pathway activating non-coding RNA 105664404 # Long non-coding RNAs with non-systematic symbols Chromatin remodeler recruitment 25842979 Protein SMARCA4, BAF170, SNF5 SMCA4_HUMAN, SMRC2_HUMAN, SNF5_HUMAN 25842979 lncTCF7 recruits the SWI/SNF complex to activate TCF7 expression and Wnt signaling. New
XIST
(details) 		12810 NCRNA00001, DXS1089, swd66, LINC00001 X inactive specific transcript 7503 # Long non-coding RNAs with non-systematic symbols Histone modifier recruitment 29685978 Protein PRC2, YY1, hnRNPK, SHARP # 29685978 Silences genes in inactive X chromosome New
ZEB2-AS1
(details) 		37149 ZEB2AS, ZEB2-AS, ZEB2NAT ZEB2 antisense RNA 1 100303491 # Antisense RNAs RNA binding 18347095 RNA mRNA # 18347095 Provides splicing of the IRES-conteining intron of ZEB2 by RNA-RNA duplex with transcript New
ZNF674-AS1
(details) 		44266 # ZNF674 antisense RNA 1 (head to head) 401588 # Antisense RNAs Modulation of protein functions, miRNA sponging 33993190, 33618674 Protein ALDOA ALDOA_HUMAN 33993190, 33618674 Promotes ALDOA binding to v-ATPase, thereby activating AMPK. Increases the expression of p21 through downregulation of miR-423-3p. New
ecCEBPA
(details) 		# ecCEBPA # # # Histone modifier recruitment, DNA modifier recruitment, Modulation of protein functions 28086087, 24107992 Protein CREBBP, EP300, DNMT1 CBP_HUMAN, EP300_HUMAN, DNMT1_HUMAN 28086087, 24107992 Inhibits DNMT1, stimulates acetyltransferase activity of CBP, promotes H3K27ac histone marks, thereby causes gene activation. New
lincRNA-Cox2
(details) 		# lincRNA-Cox2 # # # # Chromatin remodeler recruitment 26880762 DNA, Protein MyBBP1A MBB1A_HUMAN 26880762 Presumably, lincRNA-Cox2 is involved in the recruitment of the SWI/SNF complex to the late-primary genes in macrophages in response to LPS stimulation, more likely functioning as a scaffold molecule for the assembly of various SWI/SNF components. Directly interacts with MyBBP1A remodeller cofactor. New
lncAKHE
(details) 		# lncAKHE # # # # Modulation of protein functions 29706630 Protein EP400, TRRAP, YETS4 YETS4_HUMAN, TRRAP_HUMAN, EP400_HUMAN 29706630 LncAKHE interacts with YEATS4 from the histone acetylation p400-TRRAP complex results in activation of NOTCH2 signaling in hepatocellular carcinomas New
sno-lncRNAs (1-5) from the PWS critical region of chr15
(details) 		# sno-lncRNAs (1-5) from the PWS critical region of chr15 # # # # Splicing factor recruitment 22959273 Protein FOX2 RFOX2_HUMAN 22959273 Associates with alternative splicing regulator FOX2 and regulates mRNA splicing New
uc.291
(details) 		# uc.291 # # # # Modulation of protein functions 32017402 Protein ACTL6A ACL6A_HUMAN 32017402 uc.291 interactes with ACTL6A and releases the ACTL6A‐mediated repression of differentiation genes. New
uc.57
(details) 		# uc.57 # # # # RNA binding 29179465 RNA BCL11A mRNA # 29179465 uc.57 downregulates BCL11A to inhibit PI3K/AKT and MAPK signaling pathways New