| HGNC approved symbol | AIRN |
| HGNC ID | HGNC:34515 |
| Alternative names | AIR, NCRNA00088, IGF2RAS, IGF2R-AS1 |
| HGNC approved name | antisense of IGF2R non-protein coding RNA |
| Entrez gene ID | GeneID:100271873
(SSTAR profile) |
| HGNC gene family tag | # |
| HGNC gene family description | Long non-coding RNAs with non-systematic symbols |
| Function | Histone modifier recruitment, Transcription machinery interference |
| PMID for reference on function | PMID:29685978, PMID:18988810 |
| Target molecule type | DNA, Protein |
| Specific target | EHMT2 |
| Target UniProt ID | EHMT2_HUMAN |
| PMID for reference on targets and products | PMID:29685978, PMID:18988810 |
| Comment | Recruits PRC2 to distal genes Slc22a2 and Slc22a3. Recruits G9a and promotes H3K9me3 histone modification causing gene silencing. Transcription of Airn in cis reduct accessibility of its overlapping protein-coding gene Igf2r, causing the displacement of Pol II from the overlapping promoter. |
| Status of entry | New |