HGNC approved symbol | TP53COR1 |
HGNC ID | HGNC:43652 |
Alternative names | lincRNAp21, linc-p21, lincRNA-p21, Trp53cor1 |
HGNC approved name | tumor protein p53 pathway corepressor 1 |
Entrez gene ID | GeneID:102800311 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | Long non-coding RNAs with non-systematic symbols |
Function | Histone modifier recruitment, DNA modifier recruitment |
PMID for reference on function | PMID:28425074 |
Target molecule type | Protein |
Specific target | hnRNP-K, DNMT1 |
Target UniProt ID | DNMT1_HUMAN,
HNRPK_HUMAN |
PMID for reference on targets and products | PMID:28425074 |
Comment | Regulates reprogramming. Interacts with hnRNP-K and DNMT1, thereby block somatic cell reprogramming by CpG methylation at the promoters of a subset of genes and H3K9me3 maintenance at the promoters of pluripotency genes. |
Status of entry | New |