HGNC approved symbol | HOTAIR |
HGNC ID | HGNC:43984 |
Alternative names | LINC-HELLP |
HGNC approved name | HELLP associated long non-coding RNA |
Entrez gene ID | GeneID:101101692 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | Long non-coding RNAs with non-systematic symbols |
Function | Histone modifier recruitment |
PMID for reference on function | PMID:26173455 |
Target molecule type | Protein |
Specific target | EZH2 |
Target UniProt ID | EZH2_HUMAN |
PMID for reference on targets and products | PMID:26173455 |
Comment | Recruits EZH2 to silence E-Cadherin expression, thereby promoting cell migration and invasion. Represses tumor suppressor gene expression by hypermethylation of its CpG island. |
Status of entry | New |