HGNC approved symbol | PARTICL |
HGNC ID | HGNC:50886 |
Alternative names | PARTICLE |
HGNC approved name | promoter of MAT2A antisense radiation-induced circulating long non-coding RNA |
Entrez gene ID | GeneID:100630918 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | Long non-coding RNAs with non-systematic symbols |
Function | Histone modifier recruitment |
PMID for reference on function | PMID:25900080 |
Target molecule type | DNA, Protein |
Specific target | PRC2 |
Target UniProt ID | # |
PMID for reference on targets and products | PMID:25900080 |
Comment | PARTICLE forms a DNA-lncRNA triplex upstream of a MAT2A promoter CpG island causing its suppression. Presumably, the mechanism of suppression is recruitment of PRC2 on the triplex platform. |
Status of entry | New |