HGNC approved symbol | CDKN2B-AS1 |
HGNC ID | HGNC:34341 |
Alternative names | ANRIL, RP11-145E5.4, NCRNA00089, p15AS, CDKN2B-AS, PCAT12 |
HGNC approved name | CDKN2B antisense RNA 1 |
Entrez gene ID | GeneID:100048912 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | Antisense RNAs |
Function | Chromatin remodeler recruitment, Histone modifier recruitment |
PMID for reference on function | PMID:29685978, PMID:33353982, PMID:30870006 |
Target molecule type | Protein |
Specific target | YY1; BCL11 |
Target UniProt ID | TYY1_HUMAN, BC11A_HUMAN, BC11B_HUMAN |
PMID for reference on targets and products | PMID:29685978, PMID:33353982 |
Comment | Recruits Polycomb repressive complexes to promoters of CDKN2A and CDKN2B to inhibit their expression in cis and to regulate distant genes in trans. Interacts with BCL11A and mediates MAP4K1 transcription. |
Status of entry | New |