HGNC approved symbol | HOTTIP |
HGNC ID | HGNC:37461 |
Alternative names | NCRNA00213, HOXA-AS6, RP1-170O19.3, HOXA13-AS1 |
HGNC approved name | HOXA distal transcript antisense RNA |
Entrez gene ID | GeneID:100316868 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | Long non-coding RNAs with non-systematic symbols |
Function | Histone modifier recruitment |
PMID for reference on function | PMID:29685978, PMID:21423168, PMID:31786140 |
Target molecule type | Protein |
Specific target | WDR5, KMT2A |
Target UniProt ID | WDR5_HUMAN, KMT2A_HUMAN |
PMID for reference on targets and products | PMID:29685978, PMID:21423168, PMID:31786140 |
Comment | Activates HOXA genes via binding the adaptor protein WDR5 directly and targets WDR5/MLL
complexes across HOXA, driving histone H3 lysine 4 trimethylation and
gene transcription. |
Status of entry | New |