| HGNC approved symbol | LINC00968 |
| HGNC ID | HGNC:48727 |
| Alternative names | # |
| HGNC approved name | long intergenic non-protein coding RNA 968 |
| Entrez gene ID | GeneID:100507632
(SSTAR profile) |
| HGNC gene family tag | LINC |
| HGNC gene family description | Long intergenic non-protein coding RNAs |
| Function | Histone modifier recruitment, miRNA sponging |
| PMID for reference on function | PMID:30485507, PMID:30197001, PMID:30791958, PMID:33147570, PMID:33065511, PMID:33159015, PMID:31213129 |
| Target molecule type | RNA, Protein |
| Specific target | EZH2, HEY1, hsa-miR-423-5p, miR-3658, miR-21-5p |
| Target UniProt ID | EZH2_HUMAN, HEY1_HUMAN |
| PMID for reference on targets and products | PMID:30485507, PMID:30197001, PMID:30791958, PMID:33147570, PMID:33065511, PMID:33159015, PMID:31213129 |
| Comment | Recruits EZH2 to inhibit p21 expression via binding EZH2 and H3K27me3 of p21 promoter. Inhibits Wnt2/β-catenin signaling pathway via recruitment of HEY1 and silencing Wnt2. Inhibits miR-9-3p expression in an endothelial cell and promotes their proliferation and migration. Acts as molecular sponge of hsa-miR-423-5p, miR-3658, miR-21-5p. |
| Status of entry | New |