HGNC approved symbol | SMANTIS |
HGNC ID | HGNC:# |
Alternative names | NONHSAG028084.2, HSALNG0015754, Lnc-AAK1-2, MANTIS |
HGNC approved name | # |
Entrez gene ID | GeneID:107985770 (SSTAR profile) |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeler recruitment, Modulation of protein functions |
PMID for reference on function | PMID:31222221, PMID:28351900 |
Target molecule type | DNA, Protein |
Specific target | SMARCA4 |
Target UniProt ID | SMCA4_HUMAN |
PMID for reference on targets and products | PMID:31222221, PMID:28351900 |
Comment | MANTIS binds DNA at the promoters of angiogenenic genes, thereby regulates angiogenesis. Directly interacts with BRG1, and increases its ATPase activity. Regulates SOX18, SMAD6, and COUP-TFII, ICAM-1 expression |
Status of entry | New |