Lncrna info
HGNC approved symbolMAGI2-AS3
Alternative names#
HGNC approved namelncRNA p53 regulated and ESC associated 1
Entrez gene IDGeneID:101927721
(SSTAR profile)
HGNC gene family tag#
HGNC gene family descriptionLong non-coding RNAs with non-systematic symbols
FunctionHistone modifier recruitment, miRNA sponging
PMID for reference on functionPMID:27912097
Target molecule typeRNA, Protein
Specific targetmiR-31-5p, miR-25, miR-525-5p, miR-3163, miR-155, miR-141/200a, miR-374a, KDM1A
Target UniProt IDKDM1A_HUMAN
PMID for reference on targets and productsPMID:27912097
CommentActs as molecular sponge of miR-31-5p, miR-25, miR-525-5p, miR-3163, miR-155, miR-141/200a, miR-374a. MAGI2-AS3 plays an important role as a tumour suppressor by targeting Fas and FasL signalling. lncRNA MAGI2‑AS3 promotes expression of Fas and FasL in breast cancer cells. Recruits KDM1A to H3K4me2 deDNA Methylation at the RACGAP1 promoter, which ultimately decreased the expression of RACGAP1.
Status of entryNew

Expression statistics
Expression range: N/A
Mean expression: N/A
Median expression: N/A
Sample class Sample Expression (RLE-normalized CAGE tags per million)
Quantile over all genes