| HGNC approved symbol | SCML2 |
| HGNC ID | HGNC:10581 |
| HGNC approved name | sex comb on midleg-like 2 (Drosophila) |
| Entrez gene ID | GeneID:10389 (SSTAR profile) |
| UniProt AC (human) | Q9UQR0 |
| UniProt ID (human) | SCML2_HUMAN |
| Pfam domains | MBT PF02820 (67-134, 176-241) RBR PF17208 (281-321) SLED PF12140 (355-464) SAM_1 PF00536 (628-695) |
| MGI symbol | # |
| MGI ID | MGI:# |
| UniProt AC (mouse) | # |
| UniProt ID (mouse) | # |
| HGNC gene family tag | SAMD |
| HGNC gene family description | Sterile alpha motif (SAM) domain containing |
| Function | Polycomb group (PcG) protein |
| Modification | # |
| PMID for information on function | PMID:24727478 |
| Protein complex | PRC1 |
| Target molecule | # |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:24727478 |
| Comment | Scml2 is a member of the Polycomb group of proteins involved in epigenetic gene silencing. Human Scml2 is a part of a multisubunit protein complex, PRC1 (Polycomb repressive complex 1), which is responsible for maintenance of gene repression, prevention of chromatin remodeling, preservation of the "stemness" of the cell, and cell differentiation. |
| Status of entry | # |
| Expression range: | 0.0 to 71.19 |
| Mean expression: | 3.85 ± 6.4 |
| Median expression: | 1.7 |