HGNC approved symbol | A1CF |
HGNC ID | HGNC:24086 |
HGNC approved name | APOBEC1 complementation factor |
Entrez gene ID | GeneID:29974 (SSTAR profile) |
UniProt AC (human) | Q9NQ94 |
UniProt ID (human) | A1CF_HUMAN |
Pfam domains | RRM_1 PF00076 (58-126, 138-199, 233-297) DND1_DSRM PF14709 (447-522) |
MGI symbol | A1cf |
MGI ID | MGI:1917115 |
UniProt AC (mouse) | Q5YD48 |
UniProt ID (mouse) | A1CF_MOUSE |
HGNC gene family tag | RBM |
HGNC gene family description | RNA binding motif (RRM) containing |
Function | RNA modification |
Modification | RNA deamination |
PMID for information on function | PMID:10781591 |
Protein complex | APOB_mRNA_editosome |
Target molecule | RNA |
Target entity | mRNA, mC |
Product | U |
PMID for information on target | PMID:10781591 |
Comment | ASP=A1CF has three RNA-binding domains with homologies to poly(A)-binding proteins. Recombinant ASP complements recombinant APOBEC-1 to edit apoB RNA in vitro. Therefore, APOBEC-1 and ASP represent the minimal requirements for apoB mRNA editing in vitro. |
Status of entry | # |
Expression range: | 0.0 to 211.18 |
Mean expression: | 2.36 ± 16.81 |
Median expression: | 0.0 |