HGNC approved symbol | ACTR3B |
HGNC ID | HGNC:17256 |
HGNC approved name | ARP3 actin-related protein 3 homolog B (yeast) |
Entrez gene ID | GeneID:57180 (SSTAR profile) |
UniProt AC (human) | Q9P1U1 |
UniProt ID (human) | ARP3B_HUMAN |
Pfam domains | Actin PF00022 (5-237) |
MGI symbol | Actr3b |
MGI ID | MGI:2661120 |
UniProt AC (mouse) | Q641P0 |
UniProt ID (mouse) | ARP3B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:10911987 |
Protein complex | # |
Target molecule | histone |
Target entity | H2A, H3, H4 |
Product | # |
PMID for information on target | PMID:10911987 |
Comment | Act3/Arp4 can interact through the N-terminal domains of histones H3, H4, and H2A. Since Esa1 can only acetylate nucleosomal histones as part of theNuA4 complex, it has been proposed that the Act3/Arp4 subunit functions by promoting the binding of NuA4 to chromatin. |
Status of entry | # |