HGNC approved symbol | ALKBH4 |
HGNC ID | HGNC:21900 |
HGNC approved name | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (Alkylated DNA repair protein alkB homolog 4) (DNA N6-methyl adenine demethylase ALKBH4) (EC 1.14.11.51) (Lysine-specific demethylase ALKBH4) (EC 1.14.11.-) |
Entrez gene ID | GeneID:54784 (SSTAR profile) |
UniProt AC (human) | Q9NXW9 |
UniProt ID (human) | ALKB4_HUMAN |
Pfam domains | PF13532 () |
MGI symbol | Alkbh4 |
MGI ID | MGI:1919291 |
UniProt AC (mouse) | Q9D8F1 |
UniProt ID (mouse) | ALKB4_MOUSE |
HGNC gene family tag | ALKBH |
HGNC gene family description | Alkylation repair homologs |
Function | DNA modification |
Modification | DNA demethylation |
PMID for information on function | PMID:30982744 |
Protein complex | # |
Target molecule | DNA |
Target entity | m6A of DNA |
Product | A |
PMID for information on target | PMID:30982744 |
Comment | Preserves Polycomb silencing |
Status of entry | New |