HGNC approved symbol | ANP32A |
HGNC ID | HGNC:13233 |
HGNC approved name | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
Entrez gene ID | GeneID:8125 (SSTAR profile) |
UniProt AC (human) | P39687 |
UniProt ID (human) | AN32A_HUMAN |
Pfam domains | LRR_9 PF14580 (52-146) |
MGI symbol | Anp32a |
MGI ID | MGI:108447 |
UniProt AC (mouse) | O35381 |
UniProt ID (mouse) | AN32A_MOUSE |
HGNC gene family tag | ANP32 |
HGNC gene family description | ANP32 acidic nuclear phosphoproteins |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:11163245 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:11163245 |
Comment | pp32 = ANP32A is a member of a family of leucine-rich acidic nuclear proteins ( 7 and 19). Results suggest potential roles of INHAT subunits in chromatin remodeling and transcriptional regulation; INHAT complex including pp32 inhibits the HAT activity of p300/CBP and PCAF by binding to their substrate, histones. |
Status of entry | # |