HGNC approved symbol | ASH1L |
HGNC ID | HGNC:19088 |
HGNC approved name | ash1 (absent, small, or homeotic)-like (Drosophila) |
Entrez gene ID | GeneID:55870 (SSTAR profile) |
UniProt AC (human) | Q9NR48 |
UniProt ID (human) | ASH1L_HUMAN |
Pfam domains | AWS PF17907 (2105-2142) SET PF00856 (2156-2261) Bromodomain PF00439 (2462-2533) PHD_5 PF20826 (2586-2628) BAH PF01426 (2662-2798) |
MGI symbol | Ash1l |
MGI ID | MGI:2183158 |
UniProt AC (mouse) | Q99MY8 |
UniProt ID (mouse) | ASH1L_MOUSE |
HGNC gene family tag | KMT, PHF |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Zinc fingers, PHD-type |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:21239497 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K36 |
Product | H3K36me |
PMID for information on target | PMID:21239497 |
Comment | Human ASH1L specifically methylates histone H3 Lys-36. Implicates that there may be a regulatory mechanism of ASH1L histone methyltransferases. |
Status of entry | # |
Expression range: | 0.0 to 42.66 |
Mean expression: | 6.71 ± 4.94 |
Median expression: | 5.48 |