| HGNC approved symbol | ASH2L |
| HGNC ID | HGNC:744 |
| HGNC approved name | ash2 (absent, small, or homeotic)-like (Drosophila) |
| Entrez gene ID | GeneID:9070 (SSTAR profile) |
| UniProt AC (human) | Q9UBL3 |
| UniProt ID (human) | ASH2L_HUMAN |
| Pfam domains | PHD_ash2p_like PF21257 (105-159) ASH2L-like_WH PF21198 (161-266) SPRY PF00622 (421-494) |
| MGI symbol | Ash2l |
| MGI ID | MGI:1344416 |
| UniProt AC (mouse) | Q91X20 |
| UniProt ID (mouse) | ASH2L_MOUSE |
| HGNC gene family tag | PHF |
| HGNC gene family description | Zinc fingers, PHD-type |
| Function | Histone modification write cofactor |
| Modification | Histone methylation |
| PMID for information on function | PMID:21285357 |
| Protein complex | COMPASS, Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4 |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:21285357 |
| Comment | The oncoprotein Ash2L is a component of the mixed lineage leukemia (MLL) family members 1–4, Setd1A, and Setd1B mammalian histone H3K4 methyltransferase complexes and is essential to maintain global trimethylation of histone H3K4. |
| Status of entry | # |
| Expression range: | 1.87 to 149.05 |
| Mean expression: | 20.41 ± 15.12 |
| Median expression: | 17.2 |