HGNC approved symbol | AURKC |
HGNC ID | HGNC:11391 |
HGNC approved name | aurora kinase C |
Entrez gene ID | GeneID:6795 (SSTAR profile) |
UniProt AC (human) | Q9UQB9 |
UniProt ID (human) | AURKC_HUMAN |
Pfam domains | Pkinase PF00069 (43-293) |
MGI symbol | Aurkc |
MGI ID | MGI:1321119 |
UniProt AC (mouse) | O88445 |
UniProt ID (mouse) | AURKC_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:15499654 |
Protein complex | # |
Target molecule | histone |
Target entity | H3S10, H3S28 |
Product | # |
PMID for information on target | PMID:15499654 |
Comment | Aurora-C=AURKC, like Aurora-B kinase, is a chromosomal passenger protein localizing first to centromeres and then to the midzone of mitotic cells. Aurora-C transcript is expressed at a moderate level albeit about an order of magnitude lower than Aurora-B transcript in diploid human fibroblasts. |
Status of entry | # |