HGNC approved symbol | BAP1 |
HGNC ID | HGNC:950 |
HGNC approved name | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
Entrez gene ID | GeneID:8314 (SSTAR profile) |
UniProt AC (human) | Q92560 |
UniProt ID (human) | BAP1_HUMAN |
Pfam domains | Peptidase_C12 PF01088 (5-214) UCH_C PF18031 (643-688) |
MGI symbol | Bap1 |
MGI ID | MGI:1206586 |
UniProt AC (mouse) | Q99PU7 |
UniProt ID (mouse) | BAP1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase, Polycomb group (PcG) protein |
Modification | Histone deubiquitination |
PMID for information on function | PMID:20436459 |
Protein complex | PR-DUB |
Target molecule | histone |
Target entity | H2AK119ub1 |
Product | H2AK119 |
PMID for information on target | PMID:19815555, PMID:19188440, PMID:20436459 |
Comment | The Polycomb group proteins BAP1 and ASX form a conserved complex in vivo and in vitro. |
Status of entry | # |
Expression range: | 0.0 to 103.97 |
Mean expression: | 24.49 ± 10.58 |
Median expression: | 22.15 |