HGNC approved symbol | BAZ1B |
HGNC ID | HGNC:961 |
HGNC approved name | bromodomain adjacent to zinc finger domain, 1B |
Entrez gene ID | GeneID:9031 (SSTAR profile) |
UniProt AC (human) | Q9UIG0 |
UniProt ID (human) | BAZ1B_HUMAN |
Pfam domains | WAC_Acf1_DNA_bd PF10537 (22-121) WHIM1 PF15612 (726-762) WSD PF15613 (899-1026) PHD PF00628 (1187-1231) Bromodomain PF00439 (1348-1427) |
MGI symbol | Baz1b |
MGI ID | MGI:1353499 |
UniProt AC (mouse) | Q9Z277 |
UniProt ID (mouse) | BAZ1B_MOUSE |
HGNC gene family tag | PHF |
HGNC gene family description | Zinc fingers, PHD-type |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:19092802 |
Protein complex | B-WICH, WINAC |
Target molecule | histone |
Target entity | H2AXT142, H3 |
Product | H2AXY142ph |
PMID for information on target | PMID:19092802 |
Comment | WSTF=BAZ1B phosphorylates Tyr 142 of H2A.X, and WSTF activity has an important role in regulating several events that are critical for the DNA damage response. |
Status of entry | # |
Expression range: | 3.12 to 115.09 |
Mean expression: | 27.33 ± 13.07 |
Median expression: | 25.03 |