HGNC approved symbol | BRD4 |
HGNC ID | HGNC:13575 |
HGNC approved name | bromodomain containing 4 |
Entrez gene ID | GeneID:23476 (SSTAR profile) |
UniProt AC (human) | O60885 |
UniProt ID (human) | BRD4_HUMAN |
Pfam domains | Bromodomain PF00439 (70-151, 358-444) BET PF17035 (610-672) BRD4_CDT PF17105 (1324-1362) |
MGI symbol | Brd4 |
MGI ID | MGI:1888520 |
UniProt AC (mouse) | Q9ESU6 |
UniProt ID (mouse) | BRD4_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:12840145 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9, H3K14, H4K5, H4K12 |
Product | # |
PMID for information on target | PMID:12840145 |
Comment | Brd4 avidly binds to di- and tetraacetylated histone H4 and diacetylated H3, but weakly or not at all to mono- and unacetylated H3 and H4. |
Status of entry | # |
Expression range: | 4.69 to 294.71 |
Mean expression: | 40.5 ± 28.39 |
Median expression: | 34.63 |