HGNC approved symbol | BRD7 |
HGNC ID | HGNC:14310 |
HGNC approved name | bromodomain containing 7 |
Entrez gene ID | GeneID:29117 (SSTAR profile) |
UniProt AC (human) | Q9NPI1 |
UniProt ID (human) | BRD7_HUMAN |
Pfam domains | Bromodomain PF00439 (142-223) DUF3512 PF12024 (298-483) |
MGI symbol | Brd7 |
MGI ID | MGI:1349766 |
UniProt AC (mouse) | O88665 |
UniProt ID (mouse) | BRD7_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:17498659 |
Protein complex | SWI/SNF BRM-BRG1 |
Target molecule | histone |
Target entity | H3K9ac, H3K14ac, H3K8ac |
Product | # |
PMID for information on target | PMID:17498659 |
Comment | BRD7 bromodomain contains the typical left-handed four-helix bundle topology, and can bind with weak affinity to lysine-acetylated peptides derived from histone H3 with K9 or K14 acetylated and from histone H4 with K8, K12 or K16 acetylated. |
Status of entry | # |
Expression range: | 7.92 to 464.57 |
Mean expression: | 50.33 ± 31.74 |
Median expression: | 43.9 |