HGNC approved symbol | BRDT |
HGNC ID | HGNC:1105 |
HGNC approved name | bromodomain, testis-specific |
Entrez gene ID | GeneID:676 (SSTAR profile) |
UniProt AC (human) | Q58F21 |
UniProt ID (human) | BRDT_HUMAN |
Pfam domains | Bromodomain PF00439 (39-120, 277-363) BET PF17035 (509-572) BRD4_CDT PF17105 (901-947) |
MGI symbol | Brdt |
MGI ID | MGI:1891374 |
UniProt AC (mouse) | Q91Y44 |
UniProt ID (mouse) | BRDT_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:22901802 |
Protein complex | # |
Target molecule | histone |
Target entity | H4K5ac, H4K8ac |
Product | # |
PMID for information on target | PMID:22901802 |
Comment | Biochemical and crystallographic studies confirm that occupancy of the BRDT acetyl-lysine binding pocket by JQ1 prevents recognition of acetylated histone H4. |
Status of entry | # |
Expression range: | 0.0 to 122.35 |
Mean expression: | 0.65 ± 6.84 |
Median expression: | 0.0 |