HGNC approved symbol | BUB1 |
HGNC ID | HGNC:1148 |
HGNC approved name | BUB1 mitotic checkpoint serine/threonine kinase |
Entrez gene ID | GeneID:699 (SSTAR profile) |
UniProt AC (human) | O43683 |
UniProt ID (human) | BUB1_HUMAN |
Pfam domains | Mad3_BUB1_I PF08311 (8-125) Pkinase PF00069 (789-1007) |
MGI symbol | Bub1 |
MGI ID | MGI:1100510 |
UniProt AC (mouse) | O08901 |
UniProt ID (mouse) | BUB1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | Histone phosphorylation |
PMID for information on function | PMID:20929775 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AS121 |
Product | H2AS121ph |
PMID for information on target | PMID:20929775 |
Comment | Bub1 mediates histone 2A-serine 121 (H2A-S121) phosphorylation. |
Status of entry | # |
Expression range: | 0.0 to 177.28 |
Mean expression: | 19.16 ± 25.93 |
Median expression: | 7.81 |