HGNC approved symbol | CDC73 |
HGNC ID | HGNC:16783 |
HGNC approved name | cell division cycle 73 |
Entrez gene ID | GeneID:79577 (SSTAR profile) |
UniProt AC (human) | Q6P1J9 |
UniProt ID (human) | CDC73_HUMAN |
Pfam domains | CDC73_N PF16050 (1-296) CDC73_C PF05179 (358-520) |
MGI symbol | Cdc73 |
MGI ID | MGI:2384876 |
UniProt AC (mouse) | Q8JZM7 |
UniProt ID (mouse) | CDC73_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor |
Modification | Histone methylation |
PMID for information on function | # |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | # |
Comment | UniProt: PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). |
Status of entry | # |
Expression range: | 7.15 to 263.69 |
Mean expression: | 50.17 ± 27.09 |
Median expression: | 45.5 |