HGNC approved symbol | CDK9 |
HGNC ID | HGNC:1780 |
HGNC approved name | cyclin-dependent kinase 9 |
Entrez gene ID | GeneID:1025 (SSTAR profile) |
UniProt AC (human) | P50750 |
UniProt ID (human) | CDK9_HUMAN |
Pfam domains | Pkinase PF00069 (19-315) |
MGI symbol | Cdk9 |
MGI ID | MGI:1328368 |
UniProt AC (mouse) | Q99J95 |
UniProt ID (mouse) | CDK9_MOUSE |
HGNC gene family tag | CDK |
HGNC gene family description | Cyclin-dependent kinases |
Function | Histone modification cofactor |
Modification | # |
PMID for information on function | PMID:19844166 |
Protein complex | # |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | # |
Comment | CDK9 functions to guide a complex network of chromatin modifications including histone H2B monoubiquitination (H2Bub1), H3 lysine 4 trimethylation (H3K4me3) and H3K36me3. UniProt: Protein kinase involved in the regulation of transcription. Part of the complex P-TEFb involved in cotranscriptional histone modification. |
Status of entry | # |