HGNC approved symbol | CHD3 |
HGNC ID | HGNC:1918 |
HGNC approved name | chromodomain helicase DNA binding protein 3 |
Entrez gene ID | GeneID:1107 (SSTAR profile) |
UniProt AC (human) | Q12873 |
UniProt ID (human) | CHD3_HUMAN |
Pfam domains | CHDNT PF08073 (155-201) PHD PF00628 (382-423, 458-500) Chromo PF00385 (630-682) SNF2-rel_dom PF00176 (738-1034) Helicase_C PF00271 (1061-1174) DUF1087 PF06465 (1294-1350) CHDII_SANT-like PF06461 (1376-1517) CHDCT2 PF08074 (1737-1884) |
MGI symbol | Chd3 |
MGI ID | MGI:1344395 |
UniProt AC (mouse) | # |
UniProt ID (mouse) | # |
HGNC gene family tag | PHF |
HGNC gene family description | Zinc fingers, PHD-type |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:12592387 |
Protein complex | NuRD |
Target molecule | DNA |
Target entity | # |
Product | # |
PMID for information on target | PMID:12592387 |
Comment | These proteins have a DNA-binding domain as well as a chromodomain motif that can directly effect chromatin structure and gene transcription. There are currently four known members of this gene family in humans (CHD1–CHD4). |
Status of entry | # |
Expression range: | 0.0 to 212.38 |
Mean expression: | 21.28 ± 19.76 |
Median expression: | 17.33 |