HGNC approved symbol | CHD7 |
HGNC ID | HGNC:20626 |
HGNC approved name | chromodomain helicase DNA binding protein 7 |
Entrez gene ID | GeneID:55636 (SSTAR profile) |
UniProt AC (human) | Q9P2D1 |
UniProt ID (human) | CHD7_HUMAN |
Pfam domains | Chromo PF00385 (801-861, 881-935) SNF2-rel_dom PF00176 (968-1257) Helicase_C PF00271 (1291-1404) BRK PF07533 (2563-2609, 2644-2687) |
MGI symbol | Chd7 |
MGI ID | MGI:2444748 |
UniProt AC (mouse) | A2AJK6 |
UniProt ID (mouse) | CHD7_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:5201778 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:5201778 |
Comment | CHD7 protein counts several functional domains: two chromo (chromatin organization modifier), one SNF2/SWI, one helicase and two BRK domains (Figure 4). Chromo domains are implicated in the recognition of lysine-methylated histone tails and of DNA (and RNA) targets. |
Status of entry | # |
Expression range: | 0.0 to 133.02 |
Mean expression: | 6.35 ± 9.54 |
Median expression: | 3.48 |