| HGNC approved symbol | CUL2 |
| HGNC ID | HGNC:2552 |
| HGNC approved name | cullin 2 |
| Entrez gene ID | GeneID:8453 (SSTAR profile) |
| UniProt AC (human) | Q13617 |
| UniProt ID (human) | CUL2_HUMAN |
| Pfam domains | Cullin PF00888 (13-644) Cullin_Nedd8 PF10557 (675-736) |
| MGI symbol | Cul2 |
| MGI ID | MGI:1918995 |
| UniProt AC (mouse) | Q9D4H8 |
| UniProt ID (mouse) | CUL2_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Chromatin remodeling cofactor |
| Modification | # |
| PMID for information on function | # |
| Protein complex | # |
| Target molecule | chromatin |
| Target entity | HP1 (Heterochromatin protein 1) |
| Product | # |
| PMID for information on target | PMID:9122164 |
| Comment | The VHL-HP1 (heterochromatin protein 1) interaction recruits VHL to chromatin. VHL interacts with elongin B, elongin C, and cullin 2 through its α domain and these proteins form an E3 ubiquitin ligase complex. |
| Status of entry | # |
| Expression range: | 2.27 to 142.82 |
| Mean expression: | 30.57 ± 11.8 |
| Median expression: | 29.93 |