HGNC approved symbol | DNMT3B |
HGNC ID | HGNC:2979 |
HGNC approved name | DNA (cytosine-5-)-methyltransferase 3 beta |
Entrez gene ID | GeneID:1789 (SSTAR profile) |
UniProt AC (human) | Q9UBC3 |
UniProt ID (human) | DNM3B_HUMAN |
Pfam domains | PWWP PF00855 (226-309) ADD_DNMT3 PF17980 (423-471) ADDz_Dnmt3b PF21255 (478-527) DNA_methylase PF00145 (575-707) |
MGI symbol | Dnmt3b |
MGI ID | MGI:1261819 |
UniProt AC (mouse) | O88509 |
UniProt ID (mouse) | DNM3B_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | DNA modification |
Modification | DNA methylation |
PMID for information on function | PMID:10325416 |
Protein complex | # |
Target molecule | DNA |
Target entity | dhC |
Product | dhU |
PMID for information on target | PMID:10325416 |
Comment | DNA methyltransferases (Dnmt3a and Dnmt3b) in mouse methylate hemimethylated and unmethylated templates with equal efficiencies and are candidates for de novo methyltransferases. |
Status of entry | # |
Expression range: | 0.0 to 1178.99 |
Mean expression: | 14.48 ± 90.17 |
Median expression: | 1.02 |