| HGNC approved symbol | DOT1L |
| HGNC ID | HGNC:24948 |
| HGNC approved name | DOT1-like histone H3K79 methyltransferase |
| Entrez gene ID | GeneID:84444
(SSTAR profile) |
| UniProt AC (human) | Q8TEK3 |
| UniProt ID (human) | DOT1L_HUMAN |
| Pfam domains | DOT1 PF08123 (117-317) |
| MGI symbol | Dot1l |
| MGI ID | MGI:2143886 |
| UniProt AC (mouse) | - |
| UniProt ID (mouse) | - |
| HGNC gene family tag | KMT |
| HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases |
| Function | Histone modification write |
| Modification | Histone methylation |
| PMID for information on function | PMID:12123582 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K79 |
| Product | # |
| PMID for information on target | PMID:12123582 |
| Comment | Human DOT1-like (DOT1L) protein possesses intrinsic H3-K79-specific histone methyltransferase (HMTase) activity in vitro and in vivo. |
| Status of entry | # |