HGNC approved symbol | EHMT1 |
HGNC ID | HGNC:24650 |
HGNC approved name | euchromatic histone-lysine N-methyltransferase 1 |
Entrez gene ID | GeneID:79813 (SSTAR profile) |
UniProt AC (human) | Q9H9B1 |
UniProt ID (human) | EHMT1_HUMAN |
Pfam domains | EHMT1-2_CRR PF21533 (539-633) Ank_4 PF13637 (772-836) Ank_2 PF12796 (838-904, 907-990) Pre-SET PF05033 (1015-1118) SET PF00856 (1137-1243) |
MGI symbol | Ehmt1 |
MGI ID | MGI:1924933 |
UniProt AC (mouse) | Q5DW34 |
UniProt ID (mouse) | EHMT1_MOUSE |
HGNC gene family tag | KMT, ANKRD |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Ankyrin repeat domain containing |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:18264113 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | H3K9me1, H3K9me2 |
PMID for information on target | PMID:18264113 |
Comment | G9a and G9a-like protein (GLP)=EHMT1 are euchromatin-associated methyltransferases that repress transcription by mono- and dimethylating histone H3 at Lys9 (H3K9). |
Status of entry | # |
Expression range: | 0.0 to 74.09 |
Mean expression: | 12.12 ± 5.74 |
Median expression: | 11.39 |