HGNC approved symbol | EHMT2 |
HGNC ID | HGNC:14129 |
HGNC approved name | euchromatic histone-lysine N-methyltransferase 2 |
Entrez gene ID | GeneID:10919 (SSTAR profile) |
UniProt AC (human) | Q96KQ7 |
UniProt ID (human) | EHMT2_HUMAN |
Pfam domains | EHMT1-2_CRR PF21533 (447-540) Ank_2 PF12796 (655-746, 750-816) Ank PF00023 (850-882) Pre-SET PF05033 (927-1030) SET PF00856 (1049-1155) |
MGI symbol | Ehmt2 |
MGI ID | MGI:2148922 |
UniProt AC (mouse) | Q9Z148 |
UniProt ID (mouse) | EHMT2_MOUSE |
HGNC gene family tag | KMT, ANKRD |
HGNC gene family description | Chromatin-modifying enzymes / K-methyltransferases, Ankyrin repeat domain containing |
Function | Histone modification write |
Modification | Histone methylation |
PMID for information on function | PMID:18264113 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K9 |
Product | H3K9me1, H3K9me2 |
PMID for information on target | PMID:18264113 |
Comment | G9a=EHMT2 and G9a-like protein (GLP) are euchromatin-associated methyltransferases that repress transcription by mono- and dimethylating histone H3 at Lys9 (H3K9). |
Status of entry | # |
Expression range: | 0.0 to 75.11 |
Mean expression: | 18.26 ± 10.17 |
Median expression: | 16.37 |