| HGNC approved symbol | ELP6 |
| HGNC ID | HGNC:25976 |
| HGNC approved name | elongator acetyltransferase complex subunit 6 |
| Entrez gene ID | GeneID:54859
(SSTAR profile) |
| UniProt AC (human) | Q0PNE2 |
| UniProt ID (human) | ELP6_HUMAN |
| Pfam domains | ELP6 PF09807 (4-251) |
| MGI symbol | Elp6 |
| MGI ID | MGI:1919349 |
| UniProt AC (mouse) | Q8BK75 |
| UniProt ID (mouse) | ELP6_MOUSE |
| HGNC gene family tag | ELP |
| HGNC gene family description | Elongator acetyltransferase complex subunits |
| Function | Histone modification write cofactor |
| Modification | Histone acetylation |
| PMID for information on function | PMID:22854966 |
| Protein complex | Pol2 elongator |
| Target molecule | histone |
| Target entity | # |
| Product | # |
| PMID for information on target | PMID:22854966 |
| Comment | The Elongator complex is composed of 6 subunits (Elp1-Elp6) and promotes RNAPII transcript elongation through histone acetylation in the nucleus as well as tRNA modification in the cytoplasm. DERP6/ELP5 and C3ORF75/ELP6 are key players for migration, invasion and tumorigenicity of melanoma cells, as integral subunits of Elongator. |
| Status of entry | # |