| HGNC approved symbol | EP300 |
| HGNC ID | HGNC:3373 |
| HGNC approved name | E1A binding protein p300 |
| Entrez gene ID | GeneID:2033 (SSTAR profile) |
| UniProt AC (human) | Q09472 |
| UniProt ID (human) | EP300_HUMAN |
| Pfam domains | zf-TAZ PF02135 (335-415, 1734-1806) KIX PF02172 (567-648) Bromodomain PF00439 (1067-1141) RING_CBP-p300 PF06001 (1156-1194) HAT_KAT11 PF08214 (1306-1611) ZZ PF00569 (1665-1706) Creb_binding PF09030 (2015-2097) |
| MGI symbol | Ep300 |
| MGI ID | MGI:1276116 |
| UniProt AC (mouse) | B2RWS6 |
| UniProt ID (mouse) | EP300_MOUSE |
| HGNC gene family tag | KAT |
| HGNC gene family description | Chromatin-modifying enzymes / K-acetyltransferases |
| Function | Histone modification write |
| Modification | Histone acetylation |
| PMID for information on function | PMID:17065153 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H2A, H2B, H3, H4 |
| Product | # |
| PMID for information on target | PMID:17065153 |
| Comment | Acetylation of proteins by p300=EP300 histone acetyltransferase plays a critical role in the regulation of gene expression. |
| Status of entry | # |
| Expression range: | 1.44 to 264.81 |
| Mean expression: | 20.5 ± 21.52 |
| Median expression: | 14.27 |