HGNC approved symbol | EP400 |
HGNC ID | HGNC:11958 |
HGNC approved name | E1A binding protein p400 |
Entrez gene ID | GeneID:57634 (SSTAR profile) |
UniProt AC (human) | Q96L91 |
UniProt ID (human) | EP400_HUMAN |
Pfam domains | EP400_N PF15790 (30-489) HSA PF07529 (803-869, 2178-2241) SNF2-rel_dom PF00176 (1094-1372) Helicase_C PF00271 (1899-2012) |
MGI symbol | Ep400 |
MGI ID | MGI:1276124 |
UniProt AC (mouse) | Q8CHI8 |
UniProt ID (mouse) | EP400_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling, Histone modification write |
Modification | Histone acetylation |
PMID for information on function | PMID:20876283 |
Protein complex | SWR, NuA4, NuA4-related complex |
Target molecule | histone |
Target entity | # |
Product | # |
PMID for information on target | PMID:20876283 |
Comment | p400 is a novel DNA damage response protein and p400-mediated alterations in nucleosome and chromatin structure promote both chromatin ubiquitination and the accumulation of brca1 and 53BP1 at sites of DNA damage. |
Status of entry | # |
Expression range: | 3.75 to 103.47 |
Mean expression: | 28.2 ± 13.34 |
Median expression: | 25.83 |