HGNC approved symbol | HCFC1 |
HGNC ID | HGNC:4839 |
HGNC approved name | host cell factor C1 |
Entrez gene ID | GeneID:3054 (SSTAR profile) |
UniProt AC (human) | P51610 |
UniProt ID (human) | HCFC1_HUMAN |
Pfam domains | Kelch_1 PF01344 (32-69) Kelch_5 PF13854 (78-114, 319-361) Kelch_3 PF13415 (216-263) |
MGI symbol | Hcfc1 |
MGI ID | MGI:105942 |
UniProt AC (mouse) | Q61191 |
UniProt ID (mouse) | HCFC1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Chromatin remodeling |
Modification | # |
PMID for information on function | PMID:12670868 |
Protein complex | NSL, COMPASS, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7 |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:12670868 |
Comment | A series of molecular activities are associated with the N-terminal subunit of HCF-1 in HSV uninfected cells. Two of these activities are associated with opposing roles in the regulation of transcription through the modulation of chromatin structure: Sin3 HDAC and a novel human Set1/Ash2 HMT. |
Status of entry | # |
Expression range: | 2.99 to 172.36 |
Mean expression: | 40.74 ± 18.38 |
Median expression: | 36.96 |