HGNC approved symbol | HDAC1 |
HGNC ID | HGNC:4852 |
HGNC approved name | histone deacetylase 1 |
Entrez gene ID | GeneID:3065 (SSTAR profile) |
UniProt AC (human) | Q13547 |
UniProt ID (human) | HDAC1_HUMAN |
Pfam domains | Hist_deacetyl PF00850 (28-318) |
MGI symbol | Hdac1 |
MGI ID | MGI:108086 |
UniProt AC (mouse) | O09106 |
UniProt ID (mouse) | HDAC1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone acetylation |
PMID for information on function | PMID:10220385 |
Protein complex | SWI/SNF_Brm, NuRD, BHC, MeCP1, mSin3A, core HDAC, mSin3A-like complex, RING2-L3MBTL2, CREST-BRG1, LSD-CoREST |
Target molecule | histone |
Target entity | H3, H4 |
Product | # |
PMID for information on target | PMID:10220385 |
Comment | HDAC1, HDAC4, HDAC5, and HDAC6 deacetylate all four core histones equally well, though deacetylation by HDAC4 and HDAC5 is incomplete. |
Status of entry | # |