HGNC approved symbol | HDAC3 |
HGNC ID | HGNC:4854 |
HGNC approved name | histone deacetylase 3 |
Entrez gene ID | GeneID:8841 (SSTAR profile) |
UniProt AC (human) | O15379 |
UniProt ID (human) | HDAC3_HUMAN |
Pfam domains | Hist_deacetyl PF00850 (22-313) |
MGI symbol | Hdac3 |
MGI ID | MGI:1343091 |
UniProt AC (mouse) | O88895 |
UniProt ID (mouse) | HDAC3_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone acetylation |
PMID for information on function | PMID:10655483 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AKac, H2BKac, H3Kac, H4Kac |
Product | H2AK, H2BK, H3K, H4K |
PMID for information on target | PMID:10655483 |
Comment | HDAC1, HDAC2, and HDAC3 constitute a human HDAC family. All three proteins possess histone deacetylase activity, and repress transcription when bound to a promoter. |
Status of entry | # |