HGNC approved symbol | HDAC8 |
HGNC ID | HGNC:13315 |
HGNC approved name | histone deacetylase 8 |
Entrez gene ID | GeneID:55869 (SSTAR profile) |
UniProt AC (human) | Q9BY41 |
UniProt ID (human) | HDAC8_HUMAN |
Pfam domains | Hist_deacetyl PF00850 (33-320) |
MGI symbol | Hdac8 |
MGI ID | MGI:1917565 |
UniProt AC (mouse) | Q8VH37 |
UniProt ID (mouse) | HDAC8_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone acetylation |
PMID for information on function | PMID:10748112 |
Protein complex | # |
Target molecule | histone |
Target entity | H2AKac, H2BKac, H3Kac, H4Kac |
Product | H2AK, H2BK, H3K, H4K |
PMID for information on target | PMID:10748112 |
Comment | HDAC8 exhibited deacetylase activity toward acetylated histone, indicating that this protein is a bona fide histone deacetylase. |
Status of entry | # |