HGNC approved symbol | HDGFL2 |
HGNC ID | HGNC:14680 |
HGNC approved name | HDGF like 2 |
Entrez gene ID | GeneID:84717 (SSTAR profile) |
UniProt AC (human) | Q7Z4V5 |
UniProt ID (human) | HDGR2_HUMAN |
Pfam domains | PWWP PF00855 (7-86) LEDGF PF11467 (472-568) |
MGI symbol | Hdgfrp2 |
MGI ID | MGI:1194492 |
UniProt AC (mouse) | Q3UMU9 |
UniProt ID (mouse) | HDGR2_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification read |
Modification | # |
PMID for information on function | PMID:217205545 |
Protein complex | # |
Target molecule | histone |
Target entity | H3K79me3, H4K20me3, H3K36me3 |
Product | # |
PMID for information on target | PMID:217205545 |
Comment | The crystal structures of the PWWP domains from seven different human proteins and three PWWP domain complex structures with histone peptides, i.e., BRPF1-H3K36me3, HDGF2-H3K79me3 and HDGF2-H4K20me3 shows that the PWWP domain can not only bind DNA but also histones. |
Status of entry | # |