HGNC approved symbol | HLCS |
HGNC ID | HGNC:4976 |
HGNC approved name | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
Entrez gene ID | GeneID:3141 (SSTAR profile) |
UniProt AC (human) | P50747 |
UniProt ID (human) | BPL1_HUMAN |
Pfam domains | BPL_LplA_LipB PF03099 (472-603) BPL_C PF02237 (669-716) |
MGI symbol | Hlcs |
MGI ID | MGI:894646 |
UniProt AC (mouse) | Q920N2 |
UniProt ID (mouse) | BPL1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write |
Modification | # |
PMID for information on function | PMID:14613969 |
Protein complex | # |
Target molecule | histone |
Target entity | H1, H2A, H2B, H4 |
Product | # |
PMID for information on target | PMID:14613969 |
Comment | Nuclear HCS =HLCS retains its biotinylating activity and has been shown to biotinylate purified histones in vitro. |
Status of entry | # |
Expression range: | 0.0 to 35.82 |
Mean expression: | 4.8 ± 3.16 |
Median expression: | 4.25 |