HGNC approved symbol | HLTF |
HGNC ID | HGNC:11099 |
HGNC approved name | helicase-like transcription factor |
Entrez gene ID | GeneID:6596 (SSTAR profile) |
UniProt AC (human) | Q14527 |
UniProt ID (human) | HLTF_HUMAN |
Pfam domains | HIRAN PF08797 (61-154) SNF2-rel_dom PF00176 (242-720) zf-C3HC4_2 PF13923 (760-800) Helicase_C PF00271 (834-950) |
MGI symbol | Hltf |
MGI ID | MGI:1196437 |
UniProt AC (mouse) | Q6PCN7 |
UniProt ID (mouse) | HLTF_MOUSE |
HGNC gene family tag | RNF |
HGNC gene family description | RING-type (C3HC4) zinc fingers |
Function | Chromatin remodeling cofactor |
Modification | # |
PMID for information on function | PMID:18719106 |
Protein complex | # |
Target molecule | chromatin |
Target entity | # |
Product | # |
PMID for information on target | PMID:18719106 |
Comment | Acts as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
Status of entry | # |
Expression range: | 0.0 to 239.4 |
Mean expression: | 36.14 ± 31.41 |
Median expression: | 29.05 |