| HGNC approved symbol | HUWE1 |
| HGNC ID | HGNC:30892 |
| HGNC approved name | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| Entrez gene ID | GeneID:10075 (SSTAR profile) |
| UniProt AC (human) | Q7Z6Z7 |
| UniProt ID (human) | HUWE1_HUMAN |
| Pfam domains | DUF908 PF06012 (25-338) DUF913 PF06025 (404-820) domain PF22562 (1317-1355) WWE PF02825 (1617-1679) UBM PF14377 (2962-2994, 3055-3081) HECT PF00632 (4067-4373) |
| MGI symbol | Huwe1 |
| MGI ID | MGI:1926884 |
| UniProt AC (mouse) | Q7TMY8 |
| UniProt ID (mouse) | HUWE1_MOUSE |
| HGNC gene family tag | # |
| HGNC gene family description | # |
| Function | Histone modification write |
| Modification | Histone ubiquitination |
| PMID for information on function | PMID:15767685 |
| Protein complex | # |
| Target molecule | histone |
| Target entity | H3K9 |
| Product | # |
| PMID for information on target | PMID:15767685 |
| Comment | A HECT=HUWE1 domain-containing E3 that ubiquitinates histones. |
| Status of entry | # |
| Expression range: | 17.32 to 194.43 |
| Mean expression: | 59.99 ± 22.57 |
| Median expression: | 55.69 |