HGNC approved symbol | IKBKAP |
HGNC ID | HGNC:5959 |
HGNC approved name | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
Entrez gene ID | GeneID:8518 (SSTAR profile) |
UniProt AC (human) | O95163 |
UniProt ID (human) | ELP1_HUMAN |
Pfam domains | IKI3 PF04762 (2-955) |
MGI symbol | Ikbkap |
MGI ID | MGI:1914544 |
UniProt AC (mouse) | Q7TT37 |
UniProt ID (mouse) | ELP1_MOUSE |
HGNC gene family tag | ELP |
HGNC gene family description | Elongator acetyltransferase complex subunits |
Function | Scaffold protein |
Modification | # |
PMID for information on function | PMID:11818576, PMID:11714725 |
Protein complex | Pol2 elongator |
Target molecule | # |
Target entity | RNA |
Product | # |
PMID for information on target | PMID:11818576, PMID:11714725 |
Comment | The human Elongator facilitates transcription by RNA polymerase II in a chromatin- and acetyl-CoA-dependent manner. Several human homologues of the yeast Elongator subunits have been identified as subunits of the human Elongator complex, including StIP1 (STAT-interacting protein 1) and IKAP (IKK complex-associated protein) =IKBKAP. |
Status of entry | # |