| HGNC approved symbol | ING2 |
| HGNC ID | HGNC:6063 |
| HGNC approved name | inhibitor of growth family, member 2 |
| Entrez gene ID | GeneID:3622
(SSTAR profile) |
| UniProt AC (human) | Q9H160 |
| UniProt ID (human) | ING2_HUMAN |
| Pfam domains | ING PF12998 (27-122) |
| MGI symbol | Ing2 |
| MGI ID | MGI:1916510 |
| UniProt AC (mouse) | Q9ESK4 |
| UniProt ID (mouse) | ING2_MOUSE |
| HGNC gene family tag | PHF |
| HGNC gene family description | Zinc fingers, PHD-type |
| Function | Histone modification read |
| Modification | # |
| PMID for information on function | PMID:16728974 |
| Protein complex | mSin3A-like complex |
| Target molecule | histone |
| Target entity | H3K4me3 |
| Product | # |
| PMID for information on target | PMID:16728974 |
| Comment | ING2, a native subunit of a repressive mSin3a-HDAC1 histone deacetylase complex, binds with high affinity to the trimethylated species. In response to DNA damage, recognition of H3K4me3 by the ING2 PHD domain stabilizes the mSin3a-HDAC1 complex at the promoters of proliferation genes. |
| Status of entry | # |