HGNC approved symbol | JMJD6 |
HGNC ID | HGNC:19355 |
HGNC approved name | jumonji domain containing 6 |
Entrez gene ID | GeneID:23210 (SSTAR profile) |
UniProt AC (human) | Q6NYC1 |
UniProt ID (human) | JMJD6_HUMAN |
Pfam domains | JmjC PF02373 (174-288) |
MGI symbol | Jmjd6 |
MGI ID | MGI:1858910 |
UniProt AC (mouse) | Q9ERI5 |
UniProt ID (mouse) | JMJD6_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification erase |
Modification | Histone methylation |
PMID for information on function | PMID:17947579 |
Protein complex | # |
Target molecule | histone |
Target entity | H3R2me, H4R3me |
Product | H3R2, H4R3 |
PMID for information on target | PMID:17947579 |
Comment | The Jumonji domain-containing 6 protein (JMJD6) is a JmjC-containing iron- and 2-oxoglutarate-dependent dioxygenase that demethylates histone H3 at arginine 2 (H3R2) and histone H4 at arginine 3 (H4R3) in both biochemical and cell-based assays. |
Status of entry | # |