HGNC approved symbol | KANSL1 |
HGNC ID | HGNC:24565 |
HGNC approved name | KAT8 regulatory NSL complex subunit 1 |
Entrez gene ID | GeneID:284058 (SSTAR profile) |
UniProt AC (human) | Q7Z3B3 |
UniProt ID (human) | KANL1_HUMAN |
Pfam domains | PEHE PF15275 (887-1020) |
MGI symbol | Kansl1 |
MGI ID | MGI:1923969 |
UniProt AC (mouse) | Q80TG1 |
UniProt ID (mouse) | KANL1_MOUSE |
HGNC gene family tag | # |
HGNC gene family description | # |
Function | Histone modification write cofactor, Histone modification write cofactor |
Modification | Histone methylation, Histone acetylation |
PMID for information on function | PMID:20018852 |
Protein complex | NSL, CHD8, MLL2/3, MLL4/WBP7 |
Target molecule | histone |
Target entity | H4 |
Product | H4ac |
PMID for information on target | PMID:20018852 |
Comment | As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. |
Status of entry | # |